DAXXIFY IN AUSTIN AT THE BUCKINGHAM CENTER

For years, people have been using injectables for facial rejuvenation purposes. Neuromodulators (e.g., BOTOX, Xeomin, Dysport, Juveau) are injectables that individuals frequently receive to address the signs of aging that are brought on by muscle movement. While the current neuromodulators are highly effective, their results are rather short-lived, lasting approximately 3 to 4 months. However, a new, longer-lasting, peptide-powered neuromodulator from Revance Aesthetics made its debut on December 1, 2022. This new cosmetic neuromodulator is called Daxxify (aka Daxi). Daxxify has been shown in clinical studies to last at least 6 months and in some individuals as long as 9 months. Initially, Daxxify will only be available to a select group of cosmetic offices in the US. The doctors at the Buckingham Center for Facial Plastic Surgery in Austin, Texas, are proud to be among the 1% chosen to provide this revolutionary new product to their patients directly following its release.

WHO CAN ADMINISTER DAXXIFY INJECTIONS IN AUSTIN, TEXAS?

A select group of cosmetic surgeons, including those at the Buckingham Center for Facial Plastic Surgery in Austin, Texas, will receive specialized training, so they can provide Daxxify injections to their patients. Following training, the surgeons at Buckingham Center can provide Daxibotulinumtoxin injections, otherwise known as Daxxify or Daxi, to their patients.

DAXXIFY IS APPROVED FOR USE BY THE US FEDERAL DRUG ADMINISTRATION (FDA)

After three decades in development, and numerous successful clinical trials, Revance Aesthetics’ Daxibotulinumtoxin, has received approval from the FDA for addressing glabellar lines.

WHO CAN RECEIVE DAXI INJECTIONS IN AUSTIN, TEXAS?

The FDA-approved Daxi injections are designed for individuals who are 18 years of age, or older. Many people seeking neuromodulator treatment to address lines and wrinkles are in their late twenties and up to early sixties.

Millennials frequently choose to have neuromodulator injections to prevent the onset of wrinkles resulting from muscle movement. By preventing the onset of dynamic wrinkles to begin with, their likelihood of developing deep lines in the treatment areas decreases.

IS THERE ANYONE WHO SHOULD AVOID HAVING DAXXIFY INJECTIONS?

Yes, pregnant women and those who have previously experienced an adverse reaction to a neuromodulator should avoid having Daxxify injections.

WHAT IS A NEUROMODULATOR?

A neuromodulator is a neurotoxin that a cosmetic surgeon strategically injects into a particular muscle to limit its range of motion by causing the muscle to relax. Using a neurotoxin to relax specific muscles can help rejuvenate the face.

HOW DOES A NEUROTOXIN KEEP A MUSCLE FROM MOVING?

A neuromodulator injection blocks the communication signals that cause the treated muscle to move or contract. Besides rejuvenating the face, limiting the movement of muscles that contribute to the formation of dynamic wrinkles discourages deepening of fine lines and wrinkles already present in the treatment areas.

WHAT IS A DYNAMIC WRINKLE?

A dynamic wrinkle results from muscle movement and contractions, which is why relaxing specific muscles with a neuromodulator can help rejuvenate the face.

WHICH LINES AND WRINKLES CAN A SURGEON ADDRESS WITH NEUROTOXIN INJECTIONS?

Dynamic wrinkles include glabellar lines (aka 11s and frown lines), crow’s feet and the horizontal lines that develop across the forehead are the most common areas. Other less common injections can occur in neck bands, wrinkles around the mouth and muscles that cause frowning.

WHY WOULD A PATIENT CHOOSE DAXXIFY OVER THE OTHER NEUROMODULATORS AVAILABLE IN AUSTIN, TEXAS?

Following Daxxify’s release, it is likely that many patients will decide to have Daxi instead of the other neuromodulators currently available (e.g., BOTOX, Xeomin, Dysport, Juveau). The longevity of Daxi’s results, 6-9 months, is the main reason patients will choose Daxxify over the other neurotoxins. The results a cosmetic surgeon achieves with Daxi can last two to three times longer than the results achieved with the other neuromodulators currently used to treat dynamic wrinkles.

PATIENTS MAINTAIN THEIR RESULTS WITH FOLLOW-UP INJECTIONS AT THE BUCKINGHAM CENTER IN AUSTIN, TEXAS

Although the current neuromodulators offer amazing results, these results are relatively short-lived. The results a surgeon achieves with the current neurotoxins usually last about three to four months. Therefore, after receiving injections, patients who want to maintain their rejuvenated appearance must return for follow-up injections several times a year. Over time, Daxxify may be preferred because this product offers similar results, but Daxi’s results last longer. Rather than 3-4 injections per year, with Daxxify the patient will only need 1-2 per year.

HOW OFTEN DO PATIENTS WHO RECEIVE DAXXIFY INJECTIONS IN AUSTIN, TEXAS, RETURN FOR FOLLOW-UP INJECTIONS?

While most patients who receive Daxi injections will return for follow-up injections twice a year, some patients will only need to return to the Buckingham Center for Facial Plastic Surgery in Austin, Texas, for maintenance injections every nine months.

HOW FREQUENTLY CAN A PATIENT RECEIVE DAXXIFY INJECTIONS?

Patients who are not receiving any other botulinum toxin products can safely receive Daxi injections.

IS THERE ANYTHING THAT EFFECTS HOW LONG A PATIENT’S NEUROMODULATOR INJECTION RESULTS LAST?

For the most part, the longevity of a patient’s results depends on the brand of neurotoxin he or she receives and the speed of his or her metabolism. For example, individuals who have a fast metabolism may notice that they need to return to the Buckingham Center in Austin, Texas, to have their maintenance injections sooner rather than later.

WHAT MAKES DAXXIFY UNIQUE?

Daxi’s formula is the only neuromodulator that is free of animal-based components and human serum albumin (HSA). Instead of using the HSA protein and animal-based components for stability, Daxxify’s formula uses Peptide Exchange Technology (PXT), which involves the use of short chains of amino acids (i.e., peptides). This revolutionary technology lengthens the ability of botulinum A to keep the treated muscle fibers from moving, which is why Daxi’s results last longer than its competitors’ results do.

HOW DOES DAXXIFY WORK?

Just like its competitors, upon injection, Daxi delivers a form of botulinum toxin to the areas the surgeon targets. Once Daxxify takes effect, muscle movements and contractions in the treatment areas temporarily cease. Although the muscles a surgeon targets with a neurotoxin stop moving, they are not completely paralyzed.

WHY DO GLABELLAR LINES DEVELOP?

Glabellar lines are typically caused by the repetitive movement of the procerus muscle and the corrugator supercilia muscles.

SEVERAL FACTORS DETERMINE THE LIKELIHOOD THAT AN INDIVIDUAL WILL DEVELOP FROWN LINES:

• How taut an individual’s glabella skin is. This is the skin that is located between the eyebrows, just above the nose
• His or her genetics
• How frequently he or she makes facial expressions that cause movement of the procerus and corrugator supercilia muscles
• The shape of his or her face
• Use of sunscreen and good skin care

WHAT CAUSES THE PROCERUS MUSCLE AND CORRUGATOR MUSCLES TO MOVE?

As an individual makes certain facial expressions, the procerus muscle and the corrugator supercilia muscles begin to move or contract. These muscle movements and contractions cause the skin on the forehead and in between the eyebrows to move as well.

HOW DO THESE MUSCLE CONTRACTIONS CAUSE THE FORMATION OF GLABELLAR LINES?

As the procerus muscle and corrugator muscles move and contract, they compress the glabella skin and the uneven edges of the moving muscles result in the development of lines. It is the repetitive movement or contractions of these muscles that cause glabellar lines to form.

HOW EFFECTIVE ARE DAXXIFY INJECTIONS FOR THE TREATMENT OF DYNAMIC WRINKLES?

According to the clinical trials that led up to its FDA approval, the results achieved with Daxi injections are comparable to those seen with Botox injections, however Daxxify lasts twice as long.

ARE GLABELLAR LINES THE ONLY DYNAMIC WRINKLES DAXXIFY CAN ADDRESS?

At this time, Daxxify is approved by the FDA for treating moderate to severe glabellar lines. Nonetheless, most experienced cosmetic surgeons will be comfortable using Daxi off-label to address the horizontal lines across the forehead as well as the crow’s feet that develop near the outer corner of each eye.

AN INITIAL CONSULTATION FOR NEUROTOXIN INJECTIONS

Upon arrival to the Buckingham Center for Facial Plastic Surgery in Austin, Texas, the patient checks in.

After checking in, a friendly staff member escorts the patient to one of the treatment areas.

One of Buckingham Center’s surgeons examines the patient’s face and asks what he or she would like to accomplish with Daxi injections. Potential treatment areas include glabellar lines, horizontal lines on the forehead and crow’s feet.

Patients who are interested in addressing other facial issues should inform their surgeon (e.g., hollowing beneath the eyes, nasolabial folds, marionette lines). The surgeon may also be able to address these issues during the patient’s upcoming injection treatment session.

INJECTING DAXXIFY AT BUCKINGHAM CENTER IN AUSTIN, TEXAS, TO ADDRESS GLABELLAR LINES

Most patients receive five injections.

WHAT TO EXPECT DURING A TREATMENT SESSION TO ADDRESS FROWN LINES WITH DAXI:

Before treatment begins, the surgeon must identify the patient’s corrugator muscles and procerus muscle. The surgeon finds the exact location of the corrugator and procerus muscles by having the patient actively contract these muscles. To contract these muscles, the patient moves each eyebrow inward, towards the other. Then, the surgeon palpates the glabellar muscle mass.

After cleansing and sanitizing the treatment areas, the surgeon injects 0.5 mL (40 units) of Daxxify into the corrugator muscles and the procerus muscle in five different locations along the muscle.

THE CORRUGATOR MUSCLES INCLUDE:

THE RIGHT AND LEFT MEDIAL CORRUGATOR MUSCLES

This section of the corrugated muscle is located in the area above the nose and each eyebrow. The typical injection site for the treatment of frown lines is in the area above the eyebrow, close to where the eyebrow begins.

THE RIGHT AND LEFT LATERAL CORRUGATOR MUSCLES

This section of the corrugator muscle is above the eyebrow as well. This section of the corrugator muscle extends upwards and further out than the medial corrugator section does.

THERE IS ONLY ONE PROCERUS MUSCLE

The procerus muscle is located between the eyebrows.

WHEN DO DAXXIFY RESULTS BECOME EVIDENT?

With Daxi, some trial participants noticed results as early as the day after treatment. However, the majority of participants saw changes within two days of treatment.

HOW LONG DO DAXI RESULTS LAST?

The median duration for Daxi results is 6 months.

THE IMPORTANCE OF CHOOSING AN EXPERIENCED COSMETIC SURGEON

It is vital that the surgeon in Austin, Texas, who is administering Daxi injections understands the anatomy of the face and the specifics as they relate to the use of neuromodulators for treating dynamic wrinkles.

THE SURGEON MUST BE ABLE TO DETECT ANY ANATOMICAL ALTERATIONS IN THE TREATMENT AREAS

The size, precise location and activity of a muscle can vary greatly from one person to the next. For this reason, surgeons who administer Daxxify must be familiar with the anatomy in the area receiving treatment, as well as whether the patient has any anatomical alterations due to disease or previous surgical procedures.

ARE THERE ANY SIDE EFFECTS OR COMPLICATIONS ASSOCIATED WITH DAXXIFY INJECTIONS?

While possible, complications related to neurotoxin injections are rare.

According to the results attained during the clinical trials, the participants tolerated Daxi well and none of the participants experienced serious adverse events related to their treatment with Daxxify. Furthermore, Daxi’s safety profile is similar to the other neuromodulators that are already available in the aesthetics market.

POTENTIAL SIDE EFFECTS INCLUDE:

• Headaches
• A droopy eyelid (i.e., ptosis)
• Bruising near the injection sites
• Inflammation, pain, a rash, bruising and itching at the injection sites
• Asymmetrical facial features due to the neurotoxin traveling to another area
• Facial numbness

COMPLICATIONS THAT PATIENTS NEED TO WATCH FOR INCLUDE:

• Difficulty breathing
• Hives
• Dizziness
• Inflammation of the throat, lips, face or tongue

If any of the complications listed above are present, seek medical attention right away.

The best way to reduce the likelihood of experiencing a complication or an unnecessary side effect (e.g., ptosis) is to choose a surgeon with intimate knowledge related to the structure of the face. In addition, the cosmetic surgeon must have extensive experience administering neurotoxins for facial rejuvenation purposes.

WHAT HAPPENS IF A NEUROMODULATOR TRAVELS?

When a neuromodulator travels, it can cause muscles in different areas of the face to relax. Relaxing the muscles surrounding the treatment areas can cause the face to appear asymmetrical.

HOW TO KEEP A NEUROTOXIN FROM TRAVELING

Patients must avoid lying down, jumping around, bending over and massaging or manipulating the treatment areas for at least two hours following their Daxi injection treatment session at the Buckingham Center for Facial Plastic Surgery in Austin, Texas.

HOW MUCH DO DAXXIFY INJECTIONS COST?

Every patient is unique, which is why the only way Dr. Buckingham or Dr. Smith can provide a quote for injections of Daxi is with an examination during an initial consultation.

WILL HEALTH INSURANCE COVER THE COST OF NEUROTOXIN INJECTIONS?

When an individual has neurotoxin injections for aesthetic purposes, it is highly unlikely that health insurance will cover his or her treatment.

Cosmetic providers at the Buckingham Center, provide men and women with treatments to address their aesthetic concerns. The Buckingham Center team has extensive experience with injectables, including neuromodulators, and are among the 1% of cosmetic surgeons with the privilege of offering Daxi to their patients directly after its release. If you are interested in receiving Daxxify injections, and you are in the Austin, Texas, area, or you plan to visit, contact the Buckingham Center for Facial Plastic Surgery today. To schedule an appointment, please call 512-401-2500. Buckingham Center is located at 6420 Bee Caves Rd, Suite 100 in Austin, Texas.